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Viagra experienced no effect on saquinavir pharmacokinetics. A much better CYP3A4 inhibitor for instance ketoconazole or itraconazole may be expected to acquire bigger result than that seen with saquinavir. Population pharmacokinetic facts from patients in clinical trials also indicated a reduction in sildenafil clearance when it had been co-administered with CYP3A4 inhibitors (including ketoconazole, erythromycin, or cimetidine) [see DOSAGE AND ADMINISTRATION and DRUG INTERACTIONS].
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The analysis of erectile dysfunction should really involve a perseverance of likely underlying triggers and the identification of correct remedy following a whole medical assessment.
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